Ventilatory response and stability of oxygen saturation during a hypoxic challenge in very preterm infants

Preterm infants have immature control of breathing and impaired pulmonary gas exchange. We hypothesized that infants with bronchopulmonary dysplasia (BPD) have a blunted ventilatory response and peripheral oxygen saturation (SpO2 ) instability during a hypoxic challenge.

Citation:
Zannin E, Stoecklin B, Choi JY, Simpson SJ, Veneroni C, Dellaca RL, Pillow JJ. Ventilatory response and stability of oxygen saturation during a hypoxic challenge in very preterm infants. Pediatr Pulmonol. 2023

Keywords:
Bronchopulmonary dysplasia; hypoxia; infant; periodic breathing; premature; ventilatory control

Abstract:
Preterm infants have immature control of breathing and impaired pulmonary gas exchange. We hypothesized that infants with bronchopulmonary dysplasia (BPD) have a blunted ventilatory response and peripheral oxygen saturation (SpO2 ) instability during a hypoxic challenge.