Citation:
Looi K, Kicic A, Noble PB, Wang KCW. Intrauterine growth restriction predisposes to airway inflammation without disruption of epithelial integrity in postnatal male mice. J Dev Orig Health Dis. 2021;12(3): 496-504.
Keywords:
Iugr; airway epithelium; airway inflammation; tight junctions
Abstract:
Evidence from animal models demonstrate that intrauterine growth restriction (IUGR) alters airway structure and function which may affect susceptibility to disease. Airway inflammation and dysregulated epithelial barrier properties are features of asthma which have not been examined in the context of IUGR.
Intrauterine growth restriction predisposes to airway inflammation without disruption of epithelial integrity in postnatal male mice
Evidence from animal models demonstrate that intrauterine growth restriction (IUGR) alters airway structure and function which may affect susceptibility to disease. Airway inflammation and dysregulated epithelial barrier properties are features of asthma which have not been examined in the context of IUGR.