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Enteral Vitamin A for Reducing Severity of Bronchopulmonary Dysplasia: A Randomized Trial

Evidence suggests that intramuscular vitamin A reduces the risk of bronchopulmonary dysplasia (BPD) in preterm infants. Our objective was to compare enteral water-soluble vitamin A with placebo supplementation to reduce the severity of BPD in extremely preterm infants.

Citation:
Rakshasbhuvankar AA, Simmer K, Patole SK, Stoecklin B, Nathan EA, Clarke MW, Pillow JJ. Enteral Vitamin A for Reducing Severity of Bronchopulmonary Dysplasia: A Randomized Trial. Pediatrics. 2021;147(1).

Keywords:
Administration, Oral; Bronchopulmonary dysplasia; Double-Blind Method; Infant/extremely Premature/newborn; prospective Studies; Treatment Outcome; Vitamin A; therapeutic use

Abstract:
Evidence suggests that intramuscular vitamin A reduces the risk of bronchopulmonary dysplasia (BPD) in preterm infants. Our objective was to compare enteral water-soluble vitamin A with placebo supplementation to reduce the severity of BPD in extremely preterm infants.