Citation:
Wang A, Koleva P, du Toit E, Geddes DT, Munblit D, Prescott SL, et al. The Milk Metabolome of Non-secretor and Lewis Negative Mothers. Front Nutr. 2021;7
Keywords:
Lewis negative; South Africa; energy metabolism; human milk; metabolome; non-secretor; oligosaccharide
Abstract:
The functional role of milk for the developing neonate is an area of great interest, and a significant amount of research has been done. However, a lot of work remains to fully understand the complexities of milk, and the variations imposed through genetics. It has previously been shown that both secretor (Se) and Lewis blood type (Le) status impacts the human milk oligosaccharide (HMO) content of human milk. While some studies have compared the non-HMO milk metabolome of Se+ and Se- women, none have reported on the non-HMO milk metabolome of Se- and Le- mothers.
The Milk Metabolome of Non-secretor and Lewis Negative Mothers
The functional role of milk for the developing neonate is an area of great interest, and a significant amount of research has been done. However, a lot of work remains to fully understand the complexities of milk, and the variations imposed through genetics. It has previously been shown that both secretor (Se) and Lewis blood type (Le) status impacts the human milk oligosaccharide (HMO) content of human milk. While some studies have compared the non-HMO milk metabolome of Se+ and Se- women, none have reported on the non-HMO milk metabolome of Se- and Le- mothers.