Citation:
Boyd RN, Ziviani J, Sakzewski L, …… Elliott C, Greaves S, Guzzetta A, Whittingham K, Valentine J, Morgan C, et al. REACH: study protocol of a randomised trial of rehabilitation very early in congenital hemiplegia. BMJ Open. 2017;7(9):e017204.
Keywords:
Bimanual therapy; brain injury; cerebral palsy; congenital hemiplegia; constraint induced movement therapy; early intervention; infant
Abstract:
Congenital hemiplegia is the most common form of cerebral palsy (CP). Children with unilateral CP show signs of upper limb asymmetry by 8 months corrected age (ca) but are frequently not referred to therapy until after 12 months ca. This study compares the efficacy of infant-friendly modified constraint-induced movement therapy (Baby mCIMT) to infant friendly bimanual therapy (Baby BIM) on upper limb, cognitive and neuroplasticity outcomes in a multisite randomised comparison trial.