Authors:
Snelling TL, Waddington CS.
Authors notes:
Expert Rev Anti-Infect Ther. 2015;13(2):145-8.
Keywords:
acellular vaccine, disease prevention, epidemic, pertussis, vaccine, whole cell vaccine
Abstract:
Several lines of evidence suggest that pertussis disease will continue to rise in countries which have switched to acellular vaccines.
While maternal vaccination is promising as a mitigating strategy it is unlikely to replace the need for a better vaccine.
In the absence of a clear alternative, a return to using whole cell vaccines, at least in part, should not be dismissed as an option without contemporary studies of feasibility and acceptability.