Authors:
Lesterhuis WJ, Bosco A, Lake RA
Authors notes:
Science Translational Medicine 6(229): 229le222
Keywords:
pathobiology,research and development,drug discovery, molecular medicine
Abstract:
The pathobiology-based approach to research and development has been the dominant paradigm for successful drug discovery over the last decades.
We propose that the molecular and cellular events that govern a resolving, rather than an evolving, disease may reveal new druggable pathways.