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Efficacy of acute myeloid leukemia therapy without stem-cell transplantation in a child with blastic plasmacytoid dendritic cell neoplasm

Our case demonstrates that AML therapy, without HSCT, can be sufficient to treat this rare disease in children.

Authors:
Hansford JR; Kotecha RS; Jevon G; Cole CH; Gottardo NG

Authors notes:
Haematologica. 2013;98(3):e30-e31

Keywords:
Blastic plasmacytoid dendritic cell neoplasm, Lymphoma, Case Study, Treatment

Abstract:
Blastic plasmacytoid dendritic cell neoplasm (BPDCN), previously known as blastic natural killer (NK) cell lymphoma, is a rare, aggressive tumor, which primarily affects the elderly (mean age 61-67 years), although it can occur at any age, including childhood.

We present a 2 1/2-year old girl treated with AML therapy who remains in first continuous complete remission two years and two months from the end of therapy.

Our case demonstrates that AML therapy, without HSCT, can be sufficient to treat this rare disease in children.