Authors:
Gangell, C. G.; Hall, G. L.
Authors notes:
Annals of Respiratory Medicine. 2012;2(1):22-27
Keywords:
Cystic fibrosis; Infants; Lung disease; Lung function; Preschool children
Abstract
The onset of lung disease in cystic fibrosis (CF) begins early in life with respiratory infection, inflammation, and structural lung damage all reported in infants with CF in the first months of life.
In this review, we have examined the role of lung function testing in infants and preschool children with CF.
In particular, we have focused on the ability of the various lung function tests to detect the presence of respiratory pathogens and structural lung disease, increased inflammation, and the onset of acute exacerbations.