Interactions between innate and adaptive immunity in asthma pathogenesis: new perspectives from studies on acute exacerbations

Atopic asthma, which is at its highest prevalence during childhood/young adulthood, represents the main focus of this review.

Authors:

Holt PG, Strickland DH

Authors notes:

Journal of Allergy and Clinical Immunology 2010;125:963-72; quiz 73-4

Keywords:
Interactions between innate, adaptive immunity, asthma pathogenesis, acute exacerbations

Abstract:
Asthma is a complex multigenic disease. The most frequently encountered form is atopic asthma, which is at its highest prevalence during childhood/young adulthood, and this represents the main focus of this review.