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Nutrition in Early Life

The vision of the Nutrition in Early Life team is to work together with the community to produce quality research, for improving our knowledge of how a mother’s diet during pregnancy and breastfeeding can improve both her and her child’s health.

The Nutrition in Early Life team conducts research investigating nutritional strategies for improved maternal and child health, including clinical trials, mechanistic studies and translatable research activities.

Our research includes identifying nutritional and environmental factors which influence the developing human immune system, particularly factors which predispose to allergic diseases (eczema, food allergy, hay fever and asthma in early childhood), as well as intervention studies for the prevention of allergic disease in childhood.

Team Highlights

  1. We have recruited more than 2000 mothers and babies in a current NHMRC funded large-scale multi-centre (Adelaide, Perth, Melbourne and Sydney) food allergy prevention study – known as the PrEggNut Study. This study is aiming to determine whether the risk of developing a food allergy can be reduced by a maternal diet rich in eggs and peanuts during pregnancy and breastfeeding.
  2. In 2023, we have completed the 1-year-old child follow-up and commenced the 5-year-old child follow-up of the NHMRC funded allergy prevention study, which recruited 652 mothers and their babies – known as the SYMBA Study. This study is aiming to determine whether the risk of a child developing any allergic diseases (including eczema, food allergy, asthma and hay fever) can be reduced by a maternal diet supplemented with prebiotics (a type of fibre) during pregnancy and breastfeeding.
  3. We have commenced recruitment for a new NHMRC funded large-scale multi-centre (Perth and Melbourne) food allergy prevention study – known as the Nuts For Babies Study. This study is aiming to determine whether the amount of nuts a mother eats during breastfeeding can reduce the risk of nut allergy development in babies.

Team leader

Debbie Palmer
Debbie Palmer

BSc BND PhD

Head, Early Life & Life-Course Health Program; Team Lead, Nutrition in Early Life

Team members (6)

Anita Jorgensen

Anita Jorgensen

National PrEggNut Study Coordinator

Emma Prescott

Emma Prescott

SYMBA Study Coordinator

Summer Walker

Summer Walker

Research Assistant

Deborah Lawrence

Deborah Lawrence

Research Nurse

Michelle Thompson

Michelle Thompson

Research Assistant

Kelly Faulkner

Kelly Faulkner

Research Nurse

Nutrition in Early Life projects

Featured projects

The PrEggNut Study – Maternal diet rich in eggs and peanuts to reduce food allergies: a randomised controlled trial

The SYMBA Study - Promoting Gut Health (SYMBiosis) for Allergy prevention

Macronutrients in Human Milk and Early Childhood Growth—Is Protein the Main Driver?

Infant growth trajectories reflect current health status and may predict future obesity and metabolic diseases. Human milk is tailored to support optimal infant growth. However, nutrient intake rather than milk composition more accurately predicts growth outcomes. Although the role of protein leverage in infant growth is unclear, protein intake is important for early infancy growth.

Effects of pregnancy and lactation prebiotics supplementation on infant allergic disease: A randomized controlled trial

Ingestion of prebiotics during pregnancy and lactation may have immunomodulatory benefits for the developing fetal and infant immune system and provide a potential dietary strategy to reduce the risk of allergic diseases. We sought to determine whether maternal supplementation with dietary prebiotics reduces the risk of allergic outcomes in infants with hereditary risk.

Higher maternal bread and thiamine intakes are associated with increased infant allergic disease

A mother's diet during pregnancy may influence her infant's immune development. However, as potential interactions between components of our dietary intakes can make any nutritional analysis complex, here we took a multi-component dietary analysis approach.

Impaired calcium influx underlies skewed T helper cell differentiation in children with IgE-mediated food allergies

Reasons for Th2 skewing in IgE-mediated food allergies remains unclear. Clinical observations suggest impaired T cell activation may drive Th2 responses evidenced by increased atopic manifestations in liver transplant patients on tacrolimus (a calcineurin inhibitor). We aimed to assess differentiation potential, T cell activation and calcium influx of naïve CD4+ T cells in children with IgE-mediated food allergies. 

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