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Research

Genetic partitioning of interleukin-6 signalling in mice dissociates Stat3 from Smad3-mediated lung fibrosis

Idiopathic pulmonary fibrosis (IPF) is a fatal disease that is unresponsive to current therapies.

Research

The CDKL5 disorder is an independent clinical entity associated with early-onset encephalopathy

The clinical understanding of the CDKL5 disorder remains limited, with most information being derived from small patient groups seen at individual centres.

Research

Screening for rheumatic heart disease: current approaches and controversies

In endemic areas, RHD has long been a target of screening programmes that, historically, have relied on cardiac auscultation.

Research

High pneumococcal serotype specific IgG, IgG1 and IgG2 levels in serum and the middle ear of children with recurrent acute otitis media

Recurrent acute otitis media (AOM), frequently caused by Streptococcus pneumoniae, is a major paediatric health problem.

Research

Low-dose oral interferon alpha as prophylaxis against viral respiratory illness: A double-blind, parallel controlled trial

A double-blind, placebo-controlled clinical trial was conducted investigating the use of low-dose oral interferon alpha for preventing acute viral...

Research

Association between pre-eclampsia and locally derived traffic-related air pollution: A retrospective cohort study

Pre-eclampsia is a common complication of pregnancy and is a major cause of fetal maternal mortality and morbidity.

Research

Identification of Der p 23, a peritrophin-like protein, as a new major dermatophagoides pteronyssinus allergen

The house dust mite (HDM) Dermatophagoides pteronyssinus is one of most important allergen sources and a major elicitor of allergic asthma.

Research

Early Childhood Research and Indonesia's Young Children

This chapter assesses what global evidence tells us about the importance of early childhood education and development...

Research

Childhood Education and Development Services in Indonesia

Although children's later experiences can still have an effect, developments in early childhood have long-lasting effects on health, behaviour and learning...