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Research

Pneumococcal conjugate vaccination at birth in a high-risk setting: No evidence for neonatal T-cell tolerance

Concerns about the risk of inducing immune deviation-associated "neonatal tolerance" as described in mice have restricted the widespread adoption...

Research

Sex-specific associations between umbilical cord blood testosterone levels and language delay in early childhood

Preliminary evidence suggests that prenatal testosterone exposure may be associated with language delay. However, no study has examined a large sample of...

Research

TLR1/2 activation during Heterologous prime-boost vaccination (DNA-MVA) enhances CD8+ T cell responses providing

Leishmania (Viannia) parasites present particular challenges, as human and murine immune responses to infection are distinct from other Leishmania species

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Obstetric malpractice litigation and cerebral palsy in term infants

The aim of this paper is to review relevant research papers to aid practitioners involved in obstetric malpractice litigation.

Research

Maternal consumption of coffee and tea during pregnancy and risk of childhood ALL: results from an Australian case-control study

To investigate whether maternal coffee and/or tea consumption during the last 6 months of pregnancy was associated with risk of childhood ALL.

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Immediate and Longer Term Immunogenicity and Safety of a Single Dose of the Combined Haemophilus influenzae Type

Hib-primed but MenC-naive toddlers (N = 433) were randomized to receive 1 dose of Hib-MenC-TT or separate Hib-TT and MenC-CRM197 vaccines.

Research

Novel non-TCR chromosome translocations t(3;11)(q25;p13) and t(X;11)(q25;p13) activating LMO2

In T-cell acute lymphoblastic leukemia (T-ALL) cytogenetic alterations juxtapose the LIM-domain-only-2 gene (LMO2) with T-cell receptor loci.

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Population-based trends in pregnancy hypertension and pre-eclampsia: an international comparative study

The objective of this study was to compare international trends in pre-eclampsia rates and in overall pregnancy hypertension rates...

Research

Neck/shoulder pain is more strongly related to depressed mood in adolescent girls than in boys

A cross-sectional study of 1258, 14 year old girls and boys used self-report and physical examination measures to assess neck/shoulder pain in the last...

Research

The impact of single gene and chromosomal disorders on hospital admissions of children and adolescents: A population-based study

It is well recognized that genetic disease makes a significant contribution to childhood illness. Here, we present recent population data describing...