Investigators: Anthony Bosco, Anya Jones, Deb Strickland, Patrick Holt
External collaborators: Prof. Peter Sly (Director, Children's Health and Environment, Queensland Children’s Medical Research Institute, Brisbane)
Plain language summary:
The drugs currently available for treatment of severe AVB in infants have all been developed based on studies on older children and adults. However it is known that immune and inflammatory functions are immature in infants and it is unclear whether the currently available anti-inflammatory drugs are therefore appropriate for this age group. This project aims to plug this knowledge gap, and to open up new opportunities for development of better treatments targeted specifically at infants.