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Oral Insulin Trial

To see if giving insulin by mouth (in a capsule) will delay or prevent T1DM in people at increased risk of developing diabetes.

Tim Jones; Liz Davis
Study Staff: Julie Dart; Heather Roby; Adam Retterath

 

The TrialNet Oral Insulin Diabetes Prevention Study is being conducted internationally, to see if giving insulin by mouth (in a capsule) will delay or prevent T1DM in people at increased risk of developing diabetes.

Participants attend the hospital for an initial, a baseline (Randomization), a 3-month follow-up visit and then follow-up visits 6-monthly for the rest of the study. At each study visit, participants are asked questions about their health, activity, diet and about diabetes in their family and will also have a physical examination and blood tests.  At the Baseline Visit, participants are randomly assigned to receive either active treatment with insulin capsule (7.5 mg insulin) or an inactive dummy capsule called placebo.

Funders: NIDDK; NIAID; NICHD; NCRR; JDRF; ADA